2,4-Difluorobenzoyl chloride

2,4-Difluorobenzoyl chloride - Names and Identifiers

Name	2,4-Difluorobenzoyl chloride
Synonyms	GVR BF DF TIMTEC-BB SBB006623 2,4-Difluorobenzoyl 2,4-DIFLUOROBENZOYL CHLORIDE 2,4-Difluorobenzoyl Chloride 2,4-Difluorobenzoyl chloride Benzoyl chloride, 2,4-difluoro- 2,4-Difluorobenzoic acid chloride Benzoyl chloride, 2,4-difluoro- (9CI)
CAS	72482-64-5
EINECS	276-690-4
InChI	InChI=1S/C7H3ClF2O/c8-7(11)5-2-1-4(9)3-6(5)10/h1-3H

2,4-Difluorobenzoyl chloride - Physico-chemical Properties

Molecular Formula	C7H3ClF2O
Molar Mass	176.55
Density	1.437 g/mL at 25 °C (lit.)
Melting Point	70-71 °C
Boling Point	96-98 °C (15 mmHg)
Flash Point	180°F
Water Solubility	REACTS
Vapor Presure	0.0278mmHg at 25°C
Specific Gravity	1.437
BRN	4800566
Storage Condition	Inert atmosphere,Room Temperature
Sensitive	Moisture Sensitive
Refractive Index	n20/D 1.5157(lit.)
MDL	MFCD00000658

2,4-Difluorobenzoyl chloride - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	R34 - Causes burns R36/37 - Irritating to eyes and respiratory system. R29 - Contact with water liberates toxic gas
Safety Description	S23 - Do not breathe vapour. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S27 - Take off immediately all contaminated clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN 3265 8/PG 2
WGK Germany	3
HS Code	29163990
Hazard Note	Corrosive
Hazard Class	8
Packing Group	II

2,4-Difluorobenzoyl chloride - Introduction

2,4-Difluorobenzoyl chloride is an organic compound with the formula C7H3ClF2O. The following is a description of the nature, use, preparation and safety information of 2,4-Difluorobenzoyl chloride:

Nature:
-Appearance: 2,4-Difluorobenzoyl chloride is a colorless liquid.
-Melting point and boiling point: Its melting point is -5°C and boiling point is 105°C.
-Solubility: 2,4-Difluorobenzoyl chloride has good solubility in common organic solvents.
-Stability: It is unstable to heat, and should avoid high temperature and direct sunlight.

Use:
- 2,4-Difluorobenzoyl chloride is a common reagent in organic synthesis and is widely used in the preparation of organic compounds with specific functional groups. For example, it can be used to synthesize drugs, pesticides and other intermediates in organic synthesis.

Preparation Method:
-The preparation of 2,4-Difluorobenzoyl chloride is generally obtained by reacting 2,4-difluorobenzoic acid with thionyl chloride. The reaction is usually carried out at room temperature, and hydrogen chloride gas generated during the reaction is added to promote the reaction.

Safety Information:
- 2,4-Difluorobenzoyl chloride is an irritating compound that may cause irritation and burns on contact with skin and eyes.
-When using 2,4-Difluorobenzoyl chloride, pay attention to protective measures, including wearing gloves, protective glasses and protective clothing.
-During the operation, pay attention to avoid inhaling its steam or mist, and maintain good ventilation conditions.
- 2,4-Difluorobenzoyl chloride should be stored away from high temperature and fire sources, and avoid contact with oxidants and strong alkali substances.

Please note that 2,4-Difluorobenzoyl chloride should be used and handled under safe laboratory conditions and follow relevant safe operating procedures.

Last Update：2024-04-09 15:17:59